[R] how to calculate multiple meta p values

[Ana Marija]

Hello,

I would like to use this package metap
to calculate multiple o values

I have my data frame with 3 p values
> head(tt)
          RS            G           E          B
1: rs2089177   0.9986   0.7153   0.604716
2: rs4360974   0.9738   0.7838   0.430228
3: rs6502526   0.9744   0.7839   0.429160
4: rs8069906   0.7184   0.4918   0.521452
5: rs9905280   0.7205   0.4861   0.465758
6: rs4313843   0.9804   0.8522   0.474313

and data frame with corresponding weights for each of the p values
from the tt data frame

> head(df)
       wg       we             wb                RS
1 40.6325 35.39774 580.6436 rs2089177
2 40.6325 35.39774 580.6436 rs4360974
3 40.6325 35.39774 580.6436 rs6502526
4 40.6325 35.39774 580.6436 rs8069906
5 40.6325 35.39774 580.6436 rs9905280
6 40.6325 35.39774 580.6436 rs4313843

RS column is the same in df and tt

How to use this sunz() function to create a new data frame which would
look the same as tt only it would have additional column, say named
"META" which has calculated meta p values for each row

This i s example of how much would be p value in the first row:

> sumz(c(0.9986,0.7153,0.604716), weights = c(40.6325,35.39774,580.6436), na.action = na.fail)
p =  0.6940048

Thanks
Ana