[R] Use probesets with highest baseline expression for differntial gene expression in LIMMA

[ejm0091]

Hello All,
I am relatively new to R. I would like to know if there is a way to alter
LIMMA defualt options such that the package instead of averaging signal
intensities of probesets selects the probesets with highest baseline
expression/highest signal intensity?

Any help would be greatly appreciated.

Many Thanks.

Ekta Jain

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