[BioC] microarray: dealing with multi probes for one gene
Christophe Boutte
boutte at sb-roscoff.fr
Mon May 21 10:19:51 CEST 2007
Dear Bioconductors users,
I make a post doc in the oceanic research station of Roscoff (France).
I use the limma bioconductor for analysing microarray results.
There is on my microarrays three replicates for each spot (thus I use
correlation or average to deal with these values).
My problem is that we have several probes for each gene on the
microarray: we designed 1 to 5 different probes for each gene, and I do
not know how to use them:
Should I average them ? It's difficult because the number of probes vary
depending of each gene (1-5) and I cannot precise the number of "dups".
I can also use correlation, but I have the same problem of variable
number of probes.
Has somebody already dealt with this type of problem of variable
multi-probes by gene ?
thank you in advance,
Christophe Boutte
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