This is a 160 GB tab-separated .txt file. It has 9 columns and 3.25x10^9 rows. Can R handle it? Thank you. HC -- View this message in context: http://r.789695.n4.nabble.com/sqldf-for-Very-Large-Tab-Delimited-Files-tp4350555p4354556.html Sent from the R help mailing list archive at Nabble.com.