[R] How to do adjust for sex, age, genotype for a data

1Rnwb sbpurohit at gmail.com
Fri Jul 17 15:59:36 CEST 2009


Hello R gurus,

I am biologist doing biomarker research and I have a data set where I have 6
proteins and close to 3000 samples, i have to look for differences between
disease(Y) and controls(N) along with genetic risk, genotypes, sex and other
demographic info available. however i do not know any of the statistics to
do the adjustment for sex, age, genotype, genetic risk. I have been reading
in papers where the authors are talking about adjusting for age, sex,
genotype, genetic risk. The CDC website suggests for adjusting the age using
the weights, but I am not sure as this would apply to my data. one website
says that if the distribution is not equal then one has to model sex, age
and other demographic parameters as co-variates. I would appreciate if
someone can help me to understand this more clearly and provide directions
on modeling these to do my analysis. I am attaching a sample data file with
this post. Thanks
http://www.nabble.com/file/p24534963/Sample%2Bdata.csv Sample+data.csv 
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