[R] sib TDT transmission/disequilibrium test

David Duffy David.Duffy at qimr.edu.au
Wed May 31 23:18:38 CEST 2006

"Farrel Buchinsky" <fjbuch at gmail.com> wrote:
> Does anyone know if the sib TDT has been implemented in R
> 1. Spielman, R.S., and Ewens, W.J. (1998) A sibship test for linkage in the
> presence of association: the sib transmission/disequilibrium test. Am J Hum
> Genet 62, 450-458

It can be done as a conditional logistic regression (look at clogit).  I don't
think the sib TDT is as efficient as an FBAT approach, which can be applied to
that type of data.

David Duffy.

| David Duffy (MBBS PhD)                                         ,-_|\
| email: davidD at qimr.edu.au  ph: INT+61+7+3362-0217 fax: -0101  /     *
| Epidemiology Unit, Queensland Institute of Medical Research   \_,-._/
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