[BioC] SomaticSignatures

hasif [guest] guest at bioconductor.org
Sat Mar 22 22:13:22 CET 2014


Hi there,
> I am a Post-doc student started analyzing human genome data few days
> back. My aim is to find UVA signature mutations. i have done variant
> calling by GATK and was wondering how i can extract signatures using
> these call without using much programming (as I am a biologist working
> in Bioinformatics field). while doing search on web i came
> across Package ‘SomaticSignatures’. i have some questions
> can you please suggest what can help me in handling this package?
> My first aim is to use my data and find sequence context of  these variants 
> please suggest me any easy guide to start with
> 

 -- output of sessionInfo(): 

> sessionInfo()
R version 3.0.3 (2014-03-06)
Platform: i686-pc-linux-gnu (32-bit)

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base   

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