[BioC] ChIPpeakAnno question--peak aggregation over bins from TSS

Zhu, Lihua (Julie) Julie.Zhu at umassmed.edu
Thu Jan 17 21:28:38 CET 2013


Kamesh,

Would you be interested in sending me a small test input and expected output
for the new functionality? Thanks!

Best regards,

Julie


On 1/17/13 11:30 AM, "Kamesh Narasimhan" <kamesh.narasimhan at utoronto.ca>
wrote:

> Hi Julie,
> 
> Thanks a lot for your reply. Yes, it would indeed be very valuable to have
> such a an aggregate function in bioconductor. I would vote for that.
> 
> Thanks a lot
> kamesh
> 
> -----Original Message-----
> From: Zhu, Lihua (Julie) [mailto:Julie.Zhu at umassmed.edu]
> Sent: Thursday, January 17, 2013 11:09 AM
> To: Kamesh Narasimhan; bioconductor at stat.math.ethz.ch
> Subject: Re: [BioC] ChIPpeakAnno question--peak aggregation over bins from TSS
> 
> Kamesh,
> 
> Thanks for sharing the interesting idea! Currently ChIPpeakAnno does not have
> function to do that. If there is a need, we are happy to add such
> functionality.
> 
> Best regards,
> 
> Julie
> 
> 
> On 1/16/13 8:49 PM, "kamesh" <kamesh.narasimhan at utoronto.ca> wrote:
> 
>> Hi ,
>> 
>> I am new to using ChIPpeakAnno and find it to be a very useful tool
>> for ChIP-seq data processing. One question I have is, given an
>> annotated data of TSS sites, would it be possible using ChIPpeakAnno
>> to aggregate and obtain mean/median of signals (for eg: ChIP-TF
>> signal)in bins around the TSS comparable to the ACT tool referenced
>> here (http://info.gersteinlab.org/ACT_IntegratedExample).
>> 
>> Thanks
>> 
>> kamesh
>> university of Toronto
>> 
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> 



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