[BioC] edge R- p-value

Gordon K Smyth smyth at wehi.EDU.AU
Mon Jul 23 03:45:37 CEST 2012


Dear Chris,

Well, the last time I replied to you on this topic (May 6) I reminded you 
that there is no function called fitLRT, and I referred you to the 
published paper on the edgeR glm methodology.

This time I'll try referring you to the latest version of the help page 
for glmLRT, see pages 47-50 of the edgeR manual:

http://bioconductor.org/packages/2.11/bioc/manuals/edgeR/man/edgeR.pdf

This help page has been improved recently, and gives a pretty detailed 
description of what glmFit and glmLRT produce.

Best wishes
Gordon

-------------- original message ---------------
[BioC] edge R- p-value
chris Jhon cjhon217 at gmail.com
Sun Jul 22 08:30:30 CEST 2012

Dear All,

I would like to confirm that i understand correctly
when use glmFit and fitLRT ,i got the out put for expression level of each
gene as log2(sample/reference) and p-value.
The p-value is the p-value of likelihood ratio test after fitting GLM, Am 
i right?
Thank you.

Regards,
chris

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