[BioC] expression status from pvalues

[James W. MacDonald]

Hi Alyaa,

On 7/11/2012 2:59 AM, Alyaa Mahmoud wrote:
> Hi All
>
> Is there a way to determine expression status of a gene (up, down) from
> corrected p.values ?

No. The p-values are strictly between 0 and 1, so there is no way to 
discern the sign of the underlying t-statistic. This would not be true 
if you were doing a one-sided t-test, but I can't imagine a use case for 
a one-sided t-test in the context of microarray analysis.

Best,

Jim


>
> Thanks a lot
> Alyaa
>

-- 
James W. MacDonald, M.S.
Biostatistician
University of Washington
Environmental and Occupational Health Sciences
4225 Roosevelt Way NE, # 100
Seattle WA 98105-6099