[BioC] what to do with microarray outliers?

[Wei Shi]

Hi Theresa:

Maybe you can try use array weights. See ?arrayWeights in limma for more details.

Cheers,
Wei

On Apr 10, 2011, at 9:56 PM, Theresa Brandt wrote:

> Hello,
> 
>   I would like to ask what to do if there are outlying microarrays on PCA
> plot. Should I remove them from the further analysis or not?
>   I have two groups of samples and these groups are clearly separated on
> the PCA plot (first and second PC). But a few microarrays are not in the
> "correct" group.
>   What to do in a situation that one of the samples is much different from
> all the others (but technically it as a good microarray)? What would you do
> in such a situation?
> 
> Sincerely,
> Theresa
> 
> 	[[alternative HTML version deleted]]
> 
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