[BioC] hyperGTest, KEGG

ivan.borozan at utoronto.ca ivan.borozan at utoronto.ca
Fri Apr 13 21:42:39 CEST 2007


Hi,

I've used the script below to calculate over-represented KEGG  
categories however I can not get to gene ID's associated with each of  
the overrepresented KEGG terms/pathways ?

hgCutoff <- 0.01
  params <- new("KEGGHyperGParams", geneIds = selectedEntrezIds,  
universeGeneIds = entrezUniverse, annotation = "Hu19K8Build17102006",   
pvalueCutoff= hgCutoff, testDirection = "over")
hgOver <- hyperGTest(params)


summary(hgOver)

gives

   KEGGID       Pvalue OddsRatio  ExpCount Count Size
1  04360 3.197873e-05 11.175439 1.0410959     5   19
2  05214 6.071664e-04  7.510345 1.1506849     7   21
3  01030 2.025983e-03 10.447619 0.6027397     3   11


however if I do

> catToGeneId(hgOver)
Error: could not find function "catToGeneId"

My question, does catToGeneId() exist and how do I get to genes that  
are associated with each of the above pathways ?

all the best,
Ivan

R version 2.4.0 (2006-10-03)

attached base packages:
[1] "splines"   "tools"     "methods"   "stats"     "graphics"  "grDevices"
[7] "utils"     "datasets"  "base"

other attached packages:
Hu19K8Build17102006             GOstats            Category           
genefilter
             "1.1.0"             "2.0.4"             "2.0.3"            
  "1.12.0"
                KEGG                RBGL                  GO            
     graph
            "1.14.1"            "1.10.0"            "1.14.0"            
  "1.12.0"
            siggenes            multtest            survival            
  annotate
             "1.8.0"            "1.12.0"              "2.29"            
  "1.12.0"
                      Biobase
                      "1.12.1"



More information about the Bioconductor mailing list